Divulgada lista dos trials que serão apresentados no ACC12. Brasileiros são destaque em uma das sessões

Autor:Humberto Graner Moreira

O American College of Cardiology divulgou a lista dos grandes trials que serão apresentados nesse congresso. Serão ao todo 18 grandes estudos cujos resultados serão apresentados nas sessões Late-Breaking Clinical Trials, sempre muito disputadas. Destaque para o trial brasileiro BRIDGE-ACS, que será apresentado pelo Dr. Otávio Berwanger, diretor do Instituto de Ensino e Pesquisa do Hospital do Coração de São Paulo (Hcor). Esta é mais uma demonstração da força da cardiologia nacional, que, nos últimos anos, tem marcado presença com destaque nos últimos congressos internacionais.

O Cardiosource em Português estará novamente presente em Chicago com mais uma edição do Programa de Cobertura Online, trazendo todas essas novidades em tempo real. Fiquem ligados.

Vejam abaixo a lista dos Late-Breaking Clinical Trials a serem apresentados

ACC.12 Opening Session and Late-Breaking Clinical Trials
Sábado, 24 de março
Effect of Transendocardial Autologous Bone Marrow Mononuclear Cell Delivery on Functional Capacity, Left Ventricular Function and Perfusion in Chronic Ischemic

Heart Failure: The FOCUS Randomized Trial
Emerson C. Perin, James Willerson, Stephen Ellis, Timothy Henry, Carl Pepine, David Zhao, Dejian Lai, Barry Byrne, Antonis Hatzopoulos, Marc Penn, Jay Traverse, Adrian Gee, Marvin Kronenberg, Daniel Martin, James Thomas, Doris Taylor, Christopher Cogle, Sonia Skarlatos, Lem Moye, Robert Simari, Cardiovascular Cell Therapy Research Network (CCTRN), Houston, TX, USA

Evaluation of a Novel Antiplatelet Agent for Secondary Prevention in Patients with Atherosclerotic Disease: Results of the Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P): TIMI 50 Trial David A. Morrow, Brigham & Women's Hospital, Boston, MA, USA


Late-Breaking Clinical Trials II
Domigo, 25 de março

Outcomes of Non-Primary PCI at Hospitals with and without On-site Cardiac Surgery:CPORT-E Trial. Final Medical Outcomes
Thomas Aversano, Johns Hopkins University, Baltimore, MD, USA


INFUSE-AMI: A 2x2 Factorial, Multicenter, Prospective, Randomized Evaluation of Intracoronary Abciximab and Aspiration Thrombectomy in Patients Undergoing Primary PCI for Anterior STEMI

Gregg W. Stone, Akiko Maehara, Bernhard Witzenbichler, Jan Godlewski, Ecaterina Cristea, Helen Parise, Jan Henk Dembrink, Andrzej Ochala, Steven Wolff, Saqib Chowdhary, Magdi El-Omar, Thomas D Neunteuff, D. Christopher Metzger, C. Michael Gibson, Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY, USA

Randomized Comparison of Adding Cilostazol Versus Doubling the Dose of Clopidogrel after Receiving Percutaneous Coronary Intervention: The HOST-ASSURE Randomized

Trial Kyung Woo Park, Hyo Soo Kim, Hyun-Jae Kang, Bon-Kwon Koo, In-Ho Chae, Seoul National University Hospital, Seoul, South Korea 

A multifaceted Intervention to Narrow the Evidence-Based Gap in the Treatment of Acute Coronary Syndromes: Main Results from the BRIDGE-ACS Cluster Randomized Trial

Otavio Berwanger, Helio Guimaraes, Alexandre Cavalcanti, Ligia Laranjeira, Eliana Santucci, Ana Zazula, Uri Flato, Marcos Tenuta, Alessandra Kodama, Elivane Victor, Mariana Carballo, Vera Mira, Luiz Mota, Eric Peterson, Renato Lopes, Research Institute of Cardiac Hospital (HCor), Sao Paulo, Brazil, Brazilian Clinical Research Institute, Sao Paulo, Brazil

Joint American College of Cardiology/New England Journal of Medicine Late-Breaking Clinical Trials



Segunda-feira, 26 de março

CORONARY: The Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study

Andre Lamy, on behalf of the CORONARY Study Investigators, Population Health Research Institute, McMaster University, Hamilton Health Sciences, Hamilton, Canada

ACRIN PA 4005: Multicenter Randomized Controlled Study of a Rapid “Rule Out” Strategy Using CT Coronary Angiogram Versus Traditional Care for Low-Risk ED Patients with Potential Acute Coronary Syndromes

Harold Litt, Chadwick Miller, Constantine Gatsonis, Brad Snyder, Harjit Singh, Laurence Gavin, Daniel Entrikin, James Leaming, Carlos Jamis-Dow, Joan Lacomis, Judd Hollander, University of Pennsylvania, Philadelphia, PA, USA, American College of Radiology Imaging Network, Philadelphia, PA, USA American College of Radiology Imaging Network, Philadelphia, PA, USA

Oral Rivaroxaban Alone for Symptomatic Pulmonary Embolism: The EINSTEIN PE Study

Harry Roger Buller, Academic Medical Center, Amsterdam, The Netherlands


Late (≥ 2 year) Clinical and Echocardiographic Outcomes after Transcatheter vs. Surgical Aortic Valve Replacement: Results from the High-Risk Cohort of the PARTNER Trial

Martin Leon, John Webb, Jeffrey Moses, Michael Mack, D. Craig Miller, Lars Svensson, E. Murat Tuzcu, Craig Smith, for the PARTNER Trial Investigators, Columbia University Medical Center and The Cardiovascular Research Foundation, New York, NY, USA

Late-Breaking Clinical Trials IV

Segunda-feira, 26 de março


Comparison of Bariatric Surgical Procedures and Advanced Medical Therapy for the Treatment of Type 2 Diabetes in Patients with Moderate Obesity: 1-year STAMPEDE Trial Results

Philip Raymond Schauer, Sangeeta Kashyap, Kathy Wolski, Stacy Brethauer, John Kirwanj, Claire Pothier, Susan Thomas, Beth Abood, Steven Nissen, Deepak Bhatt, Cleveland Clinic, Cleveland, OH, USA

A Mendelian Randomized Controlled Trial of Long Term Reduction in Low-Density Lipoprotein Cholesterol Beginning Early in Life Brian

Anthony Ference, Nitin Mahajan, Issa Alesh, Wonsuk Yoo, Karolina K. Mirowska, Abhishek Mewada, Luis Afonso, Joel Kahn, Kim Williams, John Flack, Wayne State University School of Medicine, Detroit, MI, USA

A Randomized, Double-blind, Placebo-controlled Trial of the Safety and Efficacy of a Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 Serine Protease, REGN727/SAR236553, in Patients with Primary Hypercholesterolemia (NCT: 01288443)

James McKenney, Michael Koren, Dean Kereiakes, Corinne Hanotin, ANNE-CATHERINE FERRAND, Evan Albert Stein, Regeneron Pharmaceuticals, Incorporated, Tarrytown, NY, USA, Sanofi-aventis US

Incorporated, Bridgewater, NJ, USA Pacemaker Therapy in Patients with Neurally-mediated Syncope and Documented Asystole

Michele Brignole, on the behalf of the ISSUE-3 investigators, Ospedali del Tigullio, Lavagna, Italy

Joint American College of Cardiology/Journal of the American Medical Association Late-Breaking Clinical Trials

Terça-feira, 27 de março


Survival after PCI or CABG in Older Patients with Stable Multivessel Coronary Disease: Results from the ACCF-STS Database Collaboration on the Comparative Effectiveness of Revascularization Strategies

William S. Weintraub, Maria V. Grau-Sepulveda, Jocelyn Weiss, Sean O'Brien, Eric Peterson, Paul Kolm, Zugui Zhang, Lloyd Klein, Richard Shaw, Charles McKay, Laura Ritzenthaler, Jeffrey Popma, John Messenger, David Shahian, Frederick Grover, John Mayer, Cynthia M. Shewan, Kirk Garratt, Issam Moussa, George Dangas, Fred Edwards, American College of Cardiology, Washington, DC, USA, The Society of Thoracic Surgeons, Chicago, IL,

USA Multicenter Randomized Comparative Effectiveness Trial of Cardiac CT vs Alternative Triage Strategies in Acute Chest Pain Patients in the Emergency Department: Results from the ROMICAT II Trial

Udo Hoffmann, Quynh Truong, Hang Lee, Eric Chou, Pamela Woodard, john nagurney, James H. Pope, Thomas Hauser, Charles White, Scott Weiner, Alexander Goehler, Pearl Zakroysky, Ruth Kirby, Douglas Hayden, Stephen Wiviott, Jerome Fleg, Scott Gazelle, David Schoenfeld, James Udelson, Massachusetts General Hospital - Cardiac MR PET CT Program, Boston, MA, USA

Results of the IMMEDIATE (Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care) Trial: A Double-Blind Randomized Controlled Trial of Intravenous Glucose, Insulin, and Potassium (GIK) for Acute Coronary Syndromes in Emergency Medical Services

Harry P. Selker, Joni R. Beshansky, Patricia R. Sheehan, Robin Ruthazer, John L. Griffith, James E. Udelson, Joseph M. Massaro, Ralph B. D'Agostino, IMMEDIATE Trial Investigators, Tufts Medical Center, Boston, MA, USA

Moderate Pulmonary Embolism Treated with Thrombolysis (MOPETT Study)

Mohsen Sharifi, Curt Bay, Laura Skrocki, Farnoosh Rahimi, Mahshid Mehdipour, Arizona Cardiovascular Consultants, Mesa, AZ, USA, A.T.Still University, Mesa, AZ, USA